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crossalive

crossalive

CROSSalive predicts the RNA secondary structure in vivo using contribution from the RNA sequence and the interactive proteins. CROSSalive is able to profile the RNA structure at single nucleotide resolution and it is the first algorithm trained on in vivo structural data.



 

Submission reference: 464817


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Calculate RNA Structural Profile:

Normal mode
Expert mode (with protein contribution)


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in vivo m6a (+)
in vivo m6a (-)
in vivo A-to-I (+)
in vivo A-to-I (-)


Select model:

in vivo m6a (+)
in vivo m6a (-)


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RNA Sequences (FASTA format, please ensure that your sequences only contain A, C, G, T, and U. Do not use !@#$% etc.; the minimum required sequence length is 70 nucleotides and the maximum 5000.)


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Sample data

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Xist RepC - Profile of the RepC of Xist, one of the least methylated regions of Xist, showing a Pearson’s correlation of 0.30 with in vivo SHAPE data (Smola et al. 2016)