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CROSSalive

CROSSalive

CROSSalive predicts the RNA secondary structure in vivo using contributions from the RNA sequence and the interactions with protein partners. CROSSalive is able to profile the RNA structure at single nucleotide resolution and it is the first algorithm trained on in vivo structural data.



 

Submission reference: 348481


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RNA Sequences (FASTA format, please ensure that your sequences only contain A, C, G, T, and U. Do not use !@#$% etc.; the minimum required sequence length is 70 nucleotides and the maximum 20000.)

For very long sequences please try this version that allows submission via file upload.


Calculate RNA Structural Profile:

in vivo m6a- using RNA sequence (fast)
in vivo m6a- using RNA sequence and protein interaction prediction (accurate)
in vivo m6a+ using RNA sequence (fast)
in vivo m6a+ using RNA sequence and protein interaction prediction (accurate)


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Sample data

Just trying it out? Pre-populate the form with: (Please, check that you do not have active proxies!)

Xist RepC - Profile of the RepC of Xist, one of the least methylated regions of Xist, showing a Pearson’s correlation of 0.30 with in vivo SHAPE data (Smola et al. 2016)